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Metoclopramida dosis pediatrica inyectable plm -tolcret-cy-tolcret inyectionable dosis, which is considered as most common childhood epilepsy in India due to genetic and environmental factors, a new report published in The Lancet Pediatrics has stated. "Children from India, including Delhi, have a higher risk of having acute generalized tonic-clonic seizure in the first three months of life than those from other countries. We found an association between maternal exposure to phenobarbital, chlorpromazine, gabapentin and the Tamoxifen citrate online tricyclic antidepressant fluoxetine during pregnancy and the risk of acute generalized tonic-clonic seizure in the first three months of life in children living near an animal laboratory," Dr Subash Gupta, lead author of the study, said. India had the second highest rate of childhood epilepsy in the world (after US), according to a study by Dr Gupta's group in 2011. While some experts have speculated that the high rates of epilepsy in India are a direct result of environmental pollution, while some studies suggested a role of genetics and brain abnormalities, the study's findings pointed towards environmental triggers as the main problem. In children from Delhi, the risk of having a severe form epilepsy, which includes the most common type known as tonic-clonic seizure, increased by 21 percent and the risk of severe generalized tonic-clonic seizure increased by 27 percent. The authors state that these findings suggest there is an urgent need to understand environmental risk factors for epilepsy. Dr Gupta and his group of researchers looked at data from children diagnosed with epilepsy by their doctors and those born to mothers with epilepsy or seizures diagnosed by a specialist epilepsy team. They found that when mothers were exposed to phenobarbital, chlorpromazine, gabapentin, fluoxetine and the tricyclic antidepressant during pregnancy, risk of having a severe form epilepsy increased. The researchers, however, did not conduct a comprehensive study on the environmental exposures. They are looking into the associations in more detail with the support of National Alliance for Pregnant Women and Early Years (NaPEP), an umbrella organization of organizations supporting the rights drug store online shopping canada and well-being of women children during pregnancy. Dr Gupta stressed that the problem with environmental factors was manifold. "The risk of epilepsy depends on genetics and environment it is very important to study the environment and genetics. Also, we need to ensure the correct clinical evaluation of this population so that appropriate interventions can be initiated," he told IANS. The study will be presented at next week's Congress of the International Society for Epilepsy. Last year, Dr Subhash Gupta, vice-chancellor of IISc, Delhi, and his team had carried out a study in which mothers were exposed during pregnancy to phenobarbital, chlorpromazine, gabapentin, fluoxetine and the tricyclic antidepressant during pregnancy and their foetuses developed seizures.
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